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Showing posts with label PHARMA. Show all posts
Showing posts with label PHARMA. Show all posts

Monday, 4 February 2019

Antidote and Drug of Choice Prophylaxis of choice

ANTIDOTE AND DRUG OF CHOICE PROPHYLAXIS(Dx/Px):-

1.Drug for PCM poisoning :- N acetylecystine (mucomyst)
2. DOC for Acute Asthma:- Salbutamol
3.DOC for Chronic Asthma:- Salmetrol
4.Drug of choice for bipolar disorder:- Lithium
5.Drug of choice for mania:- Lithium
6.Drug of choice for acute mania:-Haloperidol
7.Drug of choice for chronic mania:-Lithum
8.Drug of choice for hyperkalamia:- Kayxalate/sodium natropuroside/insuline+dextrose
9.Drug of choice for Ketoacidosis:- Insuline+dextrose
10.Prophylaxis for Asthma:-Montalucast
11.Drug for Digitalis Toxicity:-Digibind
12.Drug of choice for Acute migraine:-Sumatripatan
13 Drug of choice for ADHD:-Methylphenidate(Amphetamine)
14.Drug of choice for Alzeihmers disease:-Tacrine/donepzil/Rivastigmine
15.Drug of choice for Myasthenia gravis:-Neostigmine
16.Drug of choice for Anaphylactic Shock:-Adrenaline
17.Drug of choice for Hyperthyroidism in pregnancy/Lactation:-Propylthiouracil
18.Drug of choice for Atonic Seizures:-Sodium valproate
19.Drug of choice for Febrile Seizures:-Diazepam
20.Antidote for Aspirine poisoning:-Sodium bicarbonate
21.Antidote for organophosphate poisoning:-Atropine
22.Drug of choice for Central Diabetic Insipidus:-Vasoprassin/desmopressin
23.DOC for Chemotherapy induced vomiting:-Ondasteron
24.DOC for chloroquine resistant malaria:-Quinine
25.DOC for cholera:Tetracycline
26.Antidote for Benzodiazapine poisoning:-Flumazenil
27.Antidote for Barbiturate poisoning:-Sodium bicarbonate 
28.Antidote for Atropine poisoning:-Physostigmine
29.DOC for Chese reaction:-Phentolamine
30.DOC for Acute Gout:-Indomethacin
31.DOC for Chronic Gout:-Allopurinol
32.DOC for complicated Malaria:-Artesunate
33.Antidote for Cyanide poisoning:-Amyl nitrate
34.DOC for Depression:-Any of SSRI                 drug(Citalopram,Escitalopram,Fluoetine,Paroxetine,Sertraline,Vilazodone)
35.DOC for disease modifying anti Rheumatic drug(DMARD):-Methotrexate
36.DOC for drug induced parkinson disease:-Benzhexol
37.Choice of Muscle relaxant for Endotracheal intubation:-Succinylcholine
38.Choice for Relaxant for ECT:-succinylcholine
39.Treatment of choice for severe Depression:-ECT
40.DOC for Enteric Fever:-Ceftrixone
41.DOC for Epilepsy in pregnancy:-Lamotrigine
42.Antidote for Fibrinolytics:-Aminocaproic acid
43.DOC for BPH(Benign prostate hypertrophy):-Prozosin
44.Antidote for Heparine Toxicity:-Protamine sulphate
45.prophylaxis for herpes:-Acyclovir
46.prophylaxis for rheumatic fever:-Benzathaine penicilline
47.prophylaxis for MI:-Asprine
48.DOC for Malaria:-Chloroquine 
49.DOC for hypertensive emergency:-Sodium nitroprusside
50.DOC for hypertension in pregnancy:-Lobetalol
51.DOC for Eclampsia:-Mgso4
52.DOC for Hypothyroidism:-Levothyroxin
53.DOC for hypovolemic Shock:-IV fluids
54.Antidote for Iron toxicity :-Desferoxamine
55.DOC for Methanol poisoning:-Fomepizole
56.DOC FOR Methicillin resistant staphylococcus aureus :- Vencomycin
57.Mydriatic of choice in Adults:-Tropicamide
58.Mydriatic of choice in children:-Atropine
59.DOC for syphillis:-Benzathine penicilline
60.DOC for noctural enuresis :- Desmopressin/imipramine
61.DOC for obsessive compulsive disorders:-SSRI
drug(Citalopram,Escitalopram,Fluoetine,Paroxetine,Sertraline,Vilazodone)
62.Antidote for Opiod poisoning:-Nalaxone
63. DOC for oral hypoglycemic drug in obese :- metformine
64.DOC for oral hypoglycemic drug in thin:-Sulfonylureas
65.DOC for cardiogenic Shock:-Dobutamine
66.DOC for cardiogenic Shock with Oligourea:-Dopamine
67.Doc for Status Epilepticus:-Mgso4
68.DOC for prevent surgical site infection:-Cefazolin
69.Doc for patent ductus arteriosus:-Indomethacin
70.Doc for PPH:-Carbaprost
71.Doc for Anovulation:-Clomiphene Citrate
72.Antidote for warferin:- Vita. K
73.DOC for Parkinson disease:-Levodopa+carbdopa
74.DOC for hyperprolactinemia:-Bromocriptine
75.safest ATT Drug in pregnancy:-Rifampicin
76.Drug for prevent for Vertical Transmission:-Nevirapine


Sunday, 3 June 2018

CISPLASTIN

CISPLATIN

Cisplatin is  a heavy metal complex containing an atom of platinum in he center surrounded by two ammonia molecules and two chloride atoms and it is platinum based chemotherapy drug used to treat various types of cancers.

Action and pharmacology:-
Cisplatin is thought to act by producing inter-strand and cross-links of cellular DNA in a similar manner  to bifunctional ALKYLATING AGENTS. It does not appear to be cell-cycle specific.

Half life :-25 to 49 minutes and terminal half life of 58 to 73 hours was calculated.

INDICATIONS:-METASTATIC TESTICULAR TUMORS
                            METASTATIC OVARIAN TUMOR
                           ADVANCED BLADDER CA

CONTRAINDICATION:-HYPERSENSITIVITY TO CISPLATIN OF OTHER Pt contains.
                                           pregnancy
                                            laction
                                              renal impairment
                                                hearing impirment
                                                  myelosuppression

ADMINISTRATION:-
NIDDLE OR INTRAVENOUS SETS CONTAINING ALUMINUM PARTS THAT MAY COME IN CONTACT WITH CISPLATIN SHOULD NOT BE USED FOR PREPARATION OR ADMINISTRATION. ALUMINUM REACTS WITH CISPLATIN CAUSING PERCIPITATE FORMATION AND A LOSS OF POTENCY.

DRUG INTERACTIONS:- Live vaccines (contraindicated)
                                                aspirin and alcohol (GI bleeding chances)
                                                   with ototoxic and nephrotoxic durgs.
SIDE EFFECTS :- Thinned or bittle hair
                                 loss of appetite or weight
                                 diarrhoea 
                                 nausea and vommitting 
                                 change in taste
                                  tingling sensation
                                 unusual bruising or bleeding 
                                 black,tarry stools 
                                 fever chills dizziness  or feeling of faintnesspain in back
                                 swelling of the feet 
                                 seizures 
                                 rash 
                                 shortness of breath
(Ref:- united biotech private limited)

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